Received: 12.01.2026
Accepted: 22.01.2026
Published online: 20.03.2026
UDC: 616.01-099
DOI: 10.26212/2227-1937.2026.43.63.001
POSTOPERATIVE INTRAVENOUS ADMINISTRATION OF LIDOCAINE FOR THE PREVENTION OF HEMODYNAMIC DISORDERS IN PATIENTS WITH CONCOMITANT HYPERTENSION
Muzdubayeva B.T.
National Scientific Center of Phthisiopulmonology of the Republic of Kazakhstan, Almaty, Kazakhstan
Introduction. Recovery from anesthesia is a complex process accompanied by the restoration of the body’s sensitivity to pain, internal and external stimuli. One of the key factors affecting the patient’s comfort during the awakening period is the protection of the patient from an overreaction of the sympatho-adrenal system (SAS) during tracheal extubation.
Objective. To evaluate the effectiveness of lidocaine for the prevention of postoperative hemodynamic disorders upon awakening.
Materials and Methods. A study of 67 cases of awakening after general endotracheal anesthesia, after surgical interventions performed in patients with pulmonary tuberculosis and tuberculosis of bones and joints was performed. The study used quantitative and qualitative analysis methods, including statistical analysis using the StatTech v. 2.2.0 program. Data processing was carried out using Excel.
Results. When analyzing the average blood pressure and heart rate in patients who were injected with lidocaine at a dose of 1.5 mg/kg before waking up after anesthesia, it allowed for a smoother awakening and prevented excessive increases in blood pressure and heart rate in patients with concomitant hypertension.
Discussion. Intravenous administration of amide anesthetics, in particular lidocaine, reduces the sensitivity of peripheral receptors to pain stimuli and thereby reduces the reactions of CAC upon recovery from anesthesia.
Conclusions. The data we obtained allow us to conclude that the safety of postoperative awakening and the stability of hemodynamics were at a fairly high level with lidocaine administration.
Keywords: lidocaine, awakening, mean blood pressure, heart rate, sympatho-adrenal system, arterial hypertension.
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