{"id":1490,"date":"2024-09-28T13:25:04","date_gmt":"2024-09-28T13:25:04","guid":{"rendered":"https:\/\/journal.nncf.kz\/?p=1490"},"modified":"2024-11-04T08:45:46","modified_gmt":"2024-11-04T08:45:46","slug":"clinical-course-of-severe-and-critical-coronavirus-infection-covid-19-among-pregnant-women","status":"publish","type":"post","link":"https:\/\/journal.nncf.kz\/en\/clinical-course-of-severe-and-critical-coronavirus-infection-covid-19-among-pregnant-women\/","title":{"rendered":"CLINICAL COURSE OF SEVERE AND CRITICAL CORONAVIRUS INFECTION COVID-19 AMONG PREGNANT WOMEN"},"content":{"rendered":"
\nReceived: 21.06.2024\/ Accepted: 04.09.2024\/ Published online: 28.09.2024
\n\u0423\u0414\u041a 618.3-06:578.834.1
\nDOI: 10.26212\/2227-1937.2024.40.91.002<\/a>
\nTerlikbayeva A.T.1, ORCID: https:\/\/orcid.org\/0000-0002-1777-805X
\nUrazbayeva G.G.1, ORCID: https:\/\/orcid.org\/0000-0003-1584-492X
\nAyazbekov A.K.
\n2, ORCID: https:\/\/orcid.org\/0000-0003-1277-4292
\nAbuova G.N.3, ORCID: https:\/\/orcid.org\/0000-0002-1210-2018
\nTaskynova G.N.2, ORCID: https:\/\/orcid.org\/0000-0003-3169-5610
\nShaimerdenova G.G.3, ORCID: https:\/\/orcid.org\/0000-0002-5656-0918
\n1Scientific center of obstetrics, gynecology and perinatology, Almaty, Kazakhstan
\n22Khoja Akhmet YassawiInternational Kazakh-Turkish University, Turkestan, Kazakhstan
\n3South Kazakhstan Medical Academy”, Shymkent, Kazakhstan
\nCLINICAL COURSE OF SEVERE AND CRITICAL CORONAVIRUS INFECTION COVID-19 AMONG PREGNANT WOMEN
\nAbstract:
\nBackground. The COVID-19 pandemic, which spread in 2020, is a global problem that humanity has faced. Women during
\ngestation are 3 times more likely to be admitted to the intensive care unit, 2.9 times more likely to need invasive ventilation,
\n2.4 times more likely to need extracorporeal membrane oxygenation, and 1.7 times more likely to have fatal outcomes than
\nnon-pregnant women
\nMaterials and methods. We conducted a retrospective analysis of the birth histories of 92 pregnant women and postpartum
\nwomen with COVID-19 coronavirus infection at the clinical sites of the Scientific Center for Obstetrics, Gynecology and
\nPerinatology, perinatal centers in the space of 2020.
\nResults. All patients with coronavirus infection COVID-19 were young pregnant women from the age of 20 to 42 years, at a
\ngestational age of 12 to 41 weeks, of which at full term (38-41 weeks) – 17 (18.5%), at a period of 30-37 weeks – 45 (48.9%),
\n21-29 weeks – 25 (27.2%), at 12-17 weeks – 5 (5.4%). One-way analysis of variance (ANOVA) has shown that there are
\nstatistically relevant differences in the days of hospitalization among the patients, depending on the parity of births (p<0.05).
\nComplications during pregnancy on the part of the fetus were: a threatening state of the fetus was observed among 5 (5.4%),
\nintrauterine fetal death – in 22 (23.9%), premature separation of the normally located placenta (PSNLP) was observed among
\n3 (3.3%), miscarriage among 2 (2.2%), therapeutic abortion – 1 (1.1%); 28 children (34.2%) were born prematurely, with
\nbirth weight from 510g (at 22 weeks) to 3100g (at 37 weeks).
\nConclusions. Thus, pregnant women with severe and critically severe forms of COVID-19 were predominantly urban
\nresidents, at a gestational age of 30 to 37 weeks, and were multiparous. The risk of complications did not depend on the
\nnumber of previous births, highlighting the need for special attention to this patient category regardless of their obstetric
\nhistory.
\nKeywords: COVID-19, Pregnant Women, Maternal Health, Fetal Development, Antiviral Therapy<\/div>\n
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